Take a deeper look into all the publications produced by researchers at The Dartmouth Institute.

Ollaik F, Dagher M, Bachour K, Bachour J

2019 Nov 18;doi: 10.1111/ijd.14729

Int J Dermatol|2019 Nov 18

Boyle HK, Dunsiger SI, Bohlen LC, Emerson JA, Lee HH, Stevens CJ, Williams DM

2019 Nov 16;doi: 10.1007/s10865-019-00118-0

Perceptions of the physical and social environment have been shown to be predictive of physical activity (PA) behavior. However, the mechanisms of this association have not been examined. Affective response to PA was examined as a putative mediator of the association between perceptions of the PA environment and subsequent PA behavior. As part of a PA promotion study, 59 low-active overweight or obese but otherwise healthy adults completed real-time assessments of the perceived physical and social PA environment, affective response to PA, and PA behavior over a 6-month period. As hypothesized, decreased latency to and greater duration of subsequent PA was predicted by engaging in PA with a partner (b = 17.24, SE = .45, p < .01), engaging in PA outdoors versus indoors (b = 3.70, SE = 0.67, p < .01), and perceived pleasantness of the physical (b = 0.59, SE = .17, p < .01) and social settings (b = 0.68, SE = .16, p < .01). Affective response to PA (a shift toward feeling good versus bad during PA) mediated the association between engaging in PA with a partner (a path: 0.53(.11), p < .01, b path: 0.42(.12), p < .01, ab path: 0.22(.08), 95% CI .09-.41) and perceived pleasantness of the physical (a path: .38(.02), p < .01; b path: .65(.23), p = .01; ab path: .25(.09), 95% CI .08-.43) and social setting (a path: .35(.02), p < .01; b path: .57(.23), p = .01; ab path: .20(.08), 95% CI .03-.37) and PA behavior, but not the association between engaging in PA outdoors versus indoors and PA behavior. These findings suggest that perceived environmental variables may have their effects on PA through the process of psychological hedonism.

J Behav Med|2019 Nov 16

Shaker M

2019 Nov 14;pii: S1081-1206(19)31383-3. doi: 10.1016/j.anai.2019.11.003

Ann Allergy Asthma Immunol|2019 Nov 14

Baugh CW, Levine M, Cornutt D, Wilson JW, Kwun R, Mahan CE, Pollack CV Jr, Marcolini EG, Milling TJ Jr, Peacock WF, Rosovsky RP, Wu F, Sarode R, Spyropoulos AC, Villines TC, Woods TD, McManus J, Williams J

2019 Nov 13;pii: S0196-0644(19)31181-3. doi: 10.1016/j.annemergmed.2019.09.001

Bleeding is the most common complication of anticoagulant use. The evaluation and management of the bleeding patient is a core competency of emergency medicine. As the prevalence of patients receiving anticoagulant agents and variety of anticoagulants with different mechanisms of action, pharmacokinetics, indications, and corresponding reversal agents increase, physicians and other clinicians working in the emergency department require a current and nuanced understanding of how best to assess, treat, and reverse anticoagulated patients. In this project, we convened an expert panel to create a consensus decision tree and framework for assessment of the bleeding patient receiving an anticoagulant, as well as use of anticoagulant reversal or coagulation factor replacement, and to address controversies and gaps relevant to this topic. To support decision tree interpretation, the panel also reached agreement on key definitions of life-threatening bleeding, bleeding at a critical site, and emergency surgery or urgent invasive procedure. To reach consensus recommendations, we used a structured literature review and a modified Delphi technique by an expert panel of academic and community physicians with training in emergency medicine, cardiology, hematology, internal medicine/thrombology, pharmacology, toxicology, transfusion medicine and hemostasis, neurology, and surgery, and by other key stakeholder groups.

Ann Emerg Med|2019 Nov 13

Riva-Posse P, Holtzheimer PE, Mayberg HS

2019;166:371-379doi: 10.1016/B978-0-444-64196-0.00021-2

The depressive syndrome includes a number of symptoms that are clinically diverse. Research in the past decades has consistently demonstrated that the cingulate cortex plays an essential role in these manifestations. With anatomic studies initially showing volumetric changes, followed by the insights that functional imaging and physiology contributed to neuroscience and psychiatry, the distinct areas of the cingulate subdivisions were seen to have unique contributions. The subcallosal cingulate, with its functional responsivity to mood states and to antidepressant therapies, has been identified as a central node within the mood regulation network. In this chapter, detailed descriptions of the anatomic and functional changes that are seen in depression will be discussed. Finally, a focus on the development of deep brain stimulation in the subcallosal cingulate area will be used to emphasize the conceptualization of a network model with the cingulate as a hub, where engagement of remote areas of the depression network is needed to treat depression.

Handb Clin Neurol|2019

Batsis JA, Petersen CL, Crow RS, Cook SB, Stevens CJ, Seo LM, Brooks E, Mackenzie TA

2019 Nov 4;pii: S0261-5614(19)33125-5. doi: 10.1016/j.clnu.2019.10.032

Self-reported weight change may lead to adverse outcomes. We evaluated weight change with cutpoints of low lean mass (LLM) in older adults.

Clin Nutr|2019 Nov 4

Ivatury SJ, Durand MA, Elwyn G

2019 Dec;62(12):1412-1413doi: 10.1097/DCR.0000000000001454

Dis Colon Rectum|2019 Dec

House S, Frintner MP, Leyenaar JK

2019 Nov 13;pii: hpeds.2019-0151. doi: 10.1542/hpeds.2019-0151

Pediatric hospital medicine (PHM) is a growing field recently approved by the American Board of Pediatrics as a subspecialty. Understanding factors associated with hospitalist retention is important for workforce planning. Our objective for this study was to examine the proportion of pediatric hospitalists who remained in PHM over a 5-year period and identify factors associated with retention.

Hosp Pediatr|2019 Nov 13

Ma B, Allen DW, Graham MM, Har BJ, Tyrrell B, Tan Z, Spertus JA, Brown JR, Matheny ME, Hemmelgarn BR, Pannu N, James MT

2019 Nov;12(11):e005854doi: 10.1161/CIRCOUTCOMES.119.005854

Identifying patients at increased risk of contrast-associated acute kidney injury (CA-AKI) can help target risk mitigation strategies toward these individuals during percutaneous coronary intervention. Illuminating which risk models best stratify risk is an important foundation for such quality improvement efforts.

Circ Cardiovasc Qual Outcomes|2019 Nov

Emeny RT, Chang CH, Skinner J, O'Malley AJ, Smith J, Chakraborti G, Rosen CJ, Morden NE

2019 Nov 1;2(11):e1915348doi: 10.1001/jamanetworkopen.2019.15348

Many prescription drugs increase fracture risk, which raises concern for patients receiving 2 or more such drugs concurrently. Logic suggests that risk will increase with each additional drug, but the risk of taking multiple fracture-associated drugs (FADs) is unknown.

JAMA Netw Open|2019 Nov 1


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