Take a deeper look into all the publications produced by researchers at The Dartmouth Institute.

Zeitler EP, Wang Y, Pokorney SD, Curtis J, Prutkin JM

2021 Sep 14;doi: 10.1111/pace.14361

The Medtronic Sprint Fidelis® and Abbott Riata®/Riata ST® leads are at risk of failure and are subject to FDA recall. Comparative risks of various lead management strategies during elective generator change in a multi-center population are unknown. We aim to describe patients with functional, recalled ICD leads undergoing elective generator replacement and report outcomes according to lead management strategies.

Pacing Clin Electrophysiol|2021 Sep 14

Kang R, Saunders CH, Carpenter-Song EA, Moore KO, Trooboff SW, Columbo JA, Goodney PP, Wong SL, Joga Ivatury S

2021 Oct 1;64(10):1249-1258doi: 10.1097/DCR.0000000000001917

Patient education materials are created by professional organizations to inform patients about their disease and its treatment. However, it remains unclear if these materials are appropriate for patients.

Dis Colon Rectum|2021 Oct 1

Aschbrenner KA, Mueller NM, Banerjee S, Bartels SJ

2021 Jan-Dec;2doi: 10.1177/26334895211017252

Adaptations to evidence-based practices (EBPs) are common but can impact implementation and patient outcomes. In our prior research, providers in routine care made a fidelity-inconsistent adaptation to an EBP that improved health outcomes in people with serious mental illness (SMI). The purpose of this study was to characterize the process and reasons for the adaptation using a framework for reporting adaptations and modifications to EBPs, with a focus on equity.

Implement Res Pract|2021 Jan-Dec

Meyer J, Price C, Tracey D, Sharpless L, Song Y, Madden L, Elwyn G, Altice F

2021;15:1913-1927doi: 10.2147/PPA.S315543

Women with substance use disorders (SUDs) are a key population for HIV prevention with pre-exposure prophylaxis (PrEP), though uptake is limited by awareness of PrEP, misestimation of personal HIV risk, and minimally integrated HIV prevention and addiction treatment services. Patient-centered decision aids (DA) could address these barriers to PrEP, but no extant DA for PrEP has been published, including for women with SUDs.

Patient Prefer Adherence|2021

Sharma BB, Rai K, Blunt H, Zhao W, Tosteson TD, Brooks GA

2021 Sep 10;doi: 10.1002/onco.13967

Pathogenic variants of the DPYD gene are strongly associated with grade ≥3 toxicity during fluoropyrimidine chemotherapy. We conducted a systematic review and meta-analysis to estimate the risk of treatment-related death associated with DPYD gene variants.

Oncologist|2021 Sep 10

Smulowitz PB, O'Malley AJ, Khidir H, Zaborski L, McWilliams JM, Landon BE

2021 Sep;40(9):1457-1464doi: 10.1377/hlthaff.2021.00561

Concerns about avoidance or delays in seeking emergency care during the COVID-19 pandemic are widespread, but national data on emergency department (ED) visits and subsequent rates of hospitalization and outcomes are lacking. Using data on all traditional Medicare beneficiaries in the US from October 1, 2018, to September 30, 2020, we examined trends in ED visits and rates of hospitalization and thirty-day mortality conditional on an ED visit for non-COVID-19 conditions during several stages of the pandemic and for areas that were considered COVID-19 hot spots versus those that were not. We found reductions in ED visits that were largest by the first week of April 2020 (52 percent relative decrease), with volume recovering somewhat by mid-June (25 percent relative decrease). These reductions were of similar magnitude in counties that were and were not designated as COVID-19 hot spots. There was an early increase in hospitalizations and in the relative risk for thirty-day mortality, starting with the first surge of the pandemic, peaking at just over a 2-percentage-point increase. These results suggest that patients were presenting with more serious illness, perhaps related to delays in seeking care.

Health Aff (Millwood)|2021 Sep

Barnato AE, Birkmeyer JD, Skinner JS, O'Malley AJ, Birkmeyer NJO

2021 Sep 3;doi: 10.1111/jgs.17463

We sought to determine whether dementia is associated with treatment intensity and mortality in patients hospitalized with COVID-19.

J Am Geriatr Soc|2021 Sep 3

Albert D

2021 Sep 1;:9612033211038931doi: 10.1177/09612033211038931

The paradigm that autoimmune diseases are abberations in the adaptive immune system is over 50 years old, but recent data suggest a multitude of abnormalities in the innate immune system in lupus and other autoimmune diseases. This viewpoint elaborates the reasons that I think it is time to reexamine this paradigm and shift our research focus to the innate immune system in lupus and other prototypic autoimmune diseases.

Lupus|2021 Sep 1

Spijk-de Jonge MJ, Weijers JM, Teerenstra S, Elwyn G, van de Laar MA, van Riel PL, Huis AM, Hulscher ME

2021 Aug 14;pii: S0738-3991(21)00557-7. doi: 10.1016/j.pec.2021.08.013

To evaluate the effect of an intervention to improve disease activity-based management of RA in daily clinical practice by addressing patient level barriers.

Patient Educ Couns|2021 Aug 14

Mohan D, Chang CC, Fischhoff B, Rosengart MR, Angus DC, Yealy DM, Barnato AE

2021 Aug 28;268:532-539doi: 10.1016/j.jss.2021.07.029

Under-triage in trauma remains prevalent, in part because of decisions made by physicians at non-trauma centers. We developed two digital behavior change interventions to recalibrate physician heuristics (pattern recognition), and randomized 688 emergency medicine physicians to use the interventions or to a control. In this observational follow-up, we evaluated whether exposure to the interventions changed physician performance in practice.

J Surg Res|2021 Aug 28


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