Bio
Department(s)
- Molecular and Systems Biology
- Biochemistry and Cell Biology
Education
- BA, Chemistry, Willamette University
- PhD, Analytical Chemistry, University of Washington
- Postdoc, Quantitative Proteomics, Harvard Medical School
Websites
http:
Academic Analytics
Published Research
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, Lee E, Ahmed Y
Nat Commun. 2023 Oct 5;14(1):6174. doi: 10.1038/s41467-023-41843-0. Epub 2023 Oct 5.
PMID: 37798281
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa.
Koeppen K, Hampton TH, Barnaby R, Roche C, Gerber SA, Goo YA, Cho BK, Vermilyea DM, Hogan DA, Stanton BA
Am J Physiol Lung Cell Mol Physiol. 2023 Jul 1;325(1):L54-L65. doi: 10.1152/ajplung.00150.2022. Epub 2023 May 31.
PMID: 37256658
Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression.
Bagheri M, Aisha Mohamed G, Mohamed Saleem MA, Ognjenovic NB, Lu H, Kolling FW, Wilkins OM, Das S, La Croix IS, Nagaraj SH, Muller KE, Gerber SA, Miller TW, Pattabiraman DR
bioRxiv. 2023 Apr 21; pii: 2023.04.19.537586. doi: 10.1101/2023.04.19.537586. Epub 2023 Apr 21.
PMID: 37131809
Proteomics for the Discovery of Clinical Delirium Biomarkers: A Systematic Review of Major Studies.
Wiredu K, Aduse-Poku E, Shaefi S, Gerber SA
Anesth Analg. 2023 Mar 1;136(3):422-432. doi: 10.1213/ANE.0000000000006246. Epub 2022 Dec 29.
PMID: 36580411
Intraoperative plasma proteomic changes in cardiac surgery: In search of biomarkers of post-operative delirium.
Wiredu K, O'Connor S, Naseem H, Brauer BL, Kettenbach AN, Frost HR, Shaefi S, Gerber SA
Proteomics Clin Appl. 2023 Jul;17(4):e2200066. doi: 10.1002/prca.202200066. Epub 2023 Jan 4.
PMID: 36567636
Cooperation of chromatin remodeling SWI/SNF complex and pioneer factor AP-1 shapes 3D enhancer landscapes.
Wolf BK, Zhao Y, McCray A, Hawk WH, Deary LT, Sugiarto NW, LaCroix IS, Gerber SA, Cheng C, Wang X
Nat Struct Mol Biol. 2023 Jan;30(1):10-21. doi: 10.1038/s41594-022-00880-x. Epub 2022 Dec 15.
PMID: 36522426
Evaluation of Quantification and Normalization Strategies for Phosphoprotein Phosphatase Affinity Proteomics: Application to Breast Cancer Signaling.
Brauer BL, Wiredu K, Gerber SA, Kettenbach AN
J Proteome Res. 2023 Jan 6;22(1):47-61. doi: 10.1021/acs.jproteome.2c00465. Epub 2022 Nov 30.
PMID: 36448918
Metabolic phosphatase moonlights for proteins.
Gerber SA, Kettenbach AN
Nat Cell Biol. 2022 Nov;24(11):1568-1570. doi: 10.1038/s41556-022-00993-x.
PMID: 36266487
Small changes in phospho-occupancy at the kinetochore-microtubule interface drive mitotic fidelity.
Kucharski TJ, Hards R, Vandal SE, Abad MA, Jeyaprakash AA, Kaye E, Al-Rawi A, Ly T, Godek KM, Gerber SA, Compton DA
J Cell Biol. 2022 Sep 5;221(9) doi: 10.1083/jcb.202107107. Epub 2022 Jul 25.
PMID: 35878017
Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation.
Han KJ, Mikalayeva V, Gerber SA, Kettenbach AN, Skeberdis VA, Prekeris R
Life Sci Alliance. 2022 Sep;5(9) doi: 10.26508/lsa.202101346. Epub 2022 May 5.
PMID: 35512830
Courses Taught
- Molecular and Cellular Biology Graduate Programs
- Norris Cotton Cancer Center
- Program in Experimental and Molecular Medicine
- Quantitative Biomedical Sciences
Media
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, Lee E, Ahmed Y
Nat Commun. 2023 Oct 5;14(1):6174. doi: 10.1038/s41467-023-41843-0. Epub 2023 Oct 5.
PMID: 37798281
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa.
Koeppen K, Hampton TH, Barnaby R, Roche C, Gerber SA, Goo YA, Cho BK, Vermilyea DM, Hogan DA, Stanton BA
Am J Physiol Lung Cell Mol Physiol. 2023 Jul 1;325(1):L54-L65. doi: 10.1152/ajplung.00150.2022. Epub 2023 May 31.
PMID: 37256658
Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression.
Bagheri M, Aisha Mohamed G, Mohamed Saleem MA, Ognjenovic NB, Lu H, Kolling FW, Wilkins OM, Das S, La Croix IS, Nagaraj SH, Muller KE, Gerber SA, Miller TW, Pattabiraman DR
bioRxiv. 2023 Apr 21; pii: 2023.04.19.537586. doi: 10.1101/2023.04.19.537586. Epub 2023 Apr 21.
PMID: 37131809
Proteomics for the Discovery of Clinical Delirium Biomarkers: A Systematic Review of Major Studies.
Wiredu K, Aduse-Poku E, Shaefi S, Gerber SA
Anesth Analg. 2023 Mar 1;136(3):422-432. doi: 10.1213/ANE.0000000000006246. Epub 2022 Dec 29.
PMID: 36580411
Intraoperative plasma proteomic changes in cardiac surgery: In search of biomarkers of post-operative delirium.
Wiredu K, O'Connor S, Naseem H, Brauer BL, Kettenbach AN, Frost HR, Shaefi S, Gerber SA
Proteomics Clin Appl. 2023 Jul;17(4):e2200066. doi: 10.1002/prca.202200066. Epub 2023 Jan 4.
PMID: 36567636
Cooperation of chromatin remodeling SWI/SNF complex and pioneer factor AP-1 shapes 3D enhancer landscapes.
Wolf BK, Zhao Y, McCray A, Hawk WH, Deary LT, Sugiarto NW, LaCroix IS, Gerber SA, Cheng C, Wang X
Nat Struct Mol Biol. 2023 Jan;30(1):10-21. doi: 10.1038/s41594-022-00880-x. Epub 2022 Dec 15.
PMID: 36522426
Evaluation of Quantification and Normalization Strategies for Phosphoprotein Phosphatase Affinity Proteomics: Application to Breast Cancer Signaling.
Brauer BL, Wiredu K, Gerber SA, Kettenbach AN
J Proteome Res. 2023 Jan 6;22(1):47-61. doi: 10.1021/acs.jproteome.2c00465. Epub 2022 Nov 30.
PMID: 36448918
Metabolic phosphatase moonlights for proteins.
Gerber SA, Kettenbach AN
Nat Cell Biol. 2022 Nov;24(11):1568-1570. doi: 10.1038/s41556-022-00993-x.
PMID: 36266487
Small changes in phospho-occupancy at the kinetochore-microtubule interface drive mitotic fidelity.
Kucharski TJ, Hards R, Vandal SE, Abad MA, Jeyaprakash AA, Kaye E, Al-Rawi A, Ly T, Godek KM, Gerber SA, Compton DA
J Cell Biol. 2022 Sep 5;221(9) doi: 10.1083/jcb.202107107. Epub 2022 Jul 25.
PMID: 35878017
Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation.
Han KJ, Mikalayeva V, Gerber SA, Kettenbach AN, Skeberdis VA, Prekeris R
Life Sci Alliance. 2022 Sep;5(9) doi: 10.26508/lsa.202101346. Epub 2022 May 5.
PMID: 35512830